Tetracycline can pass into breast milk and may affect bone and tooth development in a nursing infant. Do not breast-feed while you are taking tetracycline. Children younger than 8 years old should not take tetracycline. Tetracycline can cause permanent tooth discoloration and can also affect a child's growth.

What is the most common side effect of tetracyclines?

Nausea, vomiting, diarrhea, loss of appetite, mouth sores, black hairy tongue, sore throat, dizziness, headache, or rectal discomfort may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

What can tetracycline cause?

Common side effects of tetracycline include:

• Discoloration of teeth and enamel hypoplasia (young children)
• Diarrhea.
• Nausea.
• Photosensitivity.
• Stomach upset.
• Loss of appetite.
• White patches or sores inside your mouth or on your lips.
• Swollen tongue.

What does tetracycline do to children?

Clinical use of tetracyclines in children younger than 8 years of age has been limited because of the known binding of first-generation tetracyclines to teeth and bones in young children, which can lead to permanent staining of the teeth and enamel hypoplasia.

What birth defects does tetracycline cause?

It is well known that use of a tetracycline during the second or third trimesters of pregnancy can discolour the unborn baby's developing milk teeth and prevent the enamel from forming properly. This means that when the baby's milk teeth come through they might be stained grey, brown or yellow.

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22 related questions found

Why tetracycline is contraindicated in pediatric patient?

Infants and children 8 years of age and younger—Tetracyclines usually are not used in young children because tetracyclines can permanently stain teeth.

What is the most common consequence of a mother ingesting tetracycline during pregnancy?

Taking this medicine during pregnancy may affect tooth and bone development in the unborn baby. Taking tetracycline during the last half of pregnancy can cause permanent tooth discoloration later in the baby's life.

Do tetracyclines stunt growth?

Tetracycline deposits into calcium-rich developing osseous tissue thereby causing the discoloration of permanent teeth, decreased rate of enamel growth, and a decrease in linear skeletal growth rate.

What is a tetracycline baby?

Tetracycline is an antibiotic used to treat conditions such as acne and many different infections. It belongs to a group of antibiotics that includes minocycline, oxytetracycline, doxycycline, sarecyline (Seysara®), and omadacycline (Nuzyra®). Tetracycline is usually taken orally (by mouth).

Can a 2 year old take tetracycline?

Children younger than 8 years old should not take tetracycline. Tetracycline can cause permanent tooth discoloration and can also affect a child's growth.

What medication causes ototoxicity?

List of Ototoxic Medications

• Non-Steroidal Anti-Inflammatory Drugs (NSAIDs), including aspirin, ibuprofen, and naproxen.
• Certain antibiotics, including aminoglycosides.
• Certain cancer medications.
• Water pills and diuretics.
• Quinine-based medications.

What is the dental side effect of tetracycline?

Tetracycline doesn't only affect the color of teeth. Exposure to the antibiotic can also weaken tooth enamel, putting teeth at risk of decay (cavity). A cavity, or hole in the tooth, is permanent and requires a dental filling.

What is tetracycline allergy?

The most commonly reported reaction due to tetracycline administration is a fixed drug reaction. While the site of this reaction varies, including the extremities, chest, and face, and a multitude of reports describe penile lesions [10,11,12,13,14].

Which of the following microbes are regularly treated with tetracyclines?

Tetracyclines are a class of antibiotics that may be used to treat infections caused by susceptible microorganisms such as gram positive and gram negative bacteria, chlamydiae, mycoplasmata, protozoans, or rickettsiae.

What do tetracyclines treat?

Tetracycline is used to treat infections caused by bacteria including pneumonia and other respiratory tract infections; ; certain infections of skin, eye, lymphatic, intestinal, genital and urinary systems; and certain other infections that are spread by ticks, lice, mites, and infected animals.

What are the contraindications of tetracycline?

Who should not take TETRACYCLINE HCL?

• diarrhea from an infection with Clostridium difficile bacteria.
• pseudotumor cerebri, a condition with high fluid pressure in the brain.
• liver problems.
• decreased kidney function.
• pregnancy.

What is the side effect of INH?

Common side effects may include: numbness, tingling, or burning pain in your hands or feet; nausea, vomiting, upset stomach; or. abnormal liver function tests.

Does minocycline cause birth defects?

The medicine may also cause birth defects if the father is using it when his sexual partner becomes pregnant. If a pregnancy occurs while you are using this medicine, tell your doctor right away. Birth control pills may not work as well while you are using minocycline.

How does tetracycline affect bone growth?

Tetracycline impairs bone mineralization and the subsequent maturation of the mineral and matrix moieties. The percentage of highly mineralized osteons labeled with tetracycline is subnormal.

Why do macrolides cause QT prolongation?

This is not surprising, as structurally similar macrolides have also been shown to cause QT interval prolongation. The mechanism by which clarithromycin induces QT prolongation is thought to be through the inhibition of the rapidly activating delayed rectifier potassium current (I_Kr) in cardiac myocytes.

When is tetracycline contraindicated?

Tetracyclines are contraindicated in pregnancy because of the risk of hepatotoxicity in the mother, the potential for permanent discoloration of teeth in the fetus (yellow or brown in appearance), as well as impairment of fetal long bone growth.

Why does tetracycline cause discoloration?

One of the side-effects of tetracyclines is incorporation into tissues that are calcifying at the time of their administration. They have the ability to chelate calcium ions and to be incorporated into teeth, cartilage and bone, resulting in discoloration of both the primary and permanent dentitions.

What is a teratogenic effect?

Teratogens are drugs, chemicals, or even infections that can cause abnormal fetal development. There are billions of potential teratogens, but only a few agents are proven to have teratogenic effects. These effects can result in a baby being born with a birth defect.

Is tetracycline contraindicated in breastfeeding?

Summary of Use during Lactation

Short-term use of tetracycline is acceptable in nursing mothers. As a theoretical precaution, avoid prolonged or repeat courses during nursing. Monitor the infant for rash and for possible effects on the gastrointestinal flora, such as diarrhea or candidiasis (thrush, diaper rash).

Which drug may cause fetal facial malformations?

The use of aminopterin during pregnancy can lead to brain abnormalities such as anencephaly, where all or part of the brain is missing, or hydrocephalus, which is a build-up of fluid in the brain. This drug can also cause facial abnormalities such as cleft lip and cleft palate.